[Dmbu-l] Talk on Tues May 6th at 1:30pm at MCS 148, by Soha Hassoun
evimaria at bu.edu
Sat May 3 13:17:26 EDT 2014
Please join us for the (probably) last data-management talk of the
Why Engineering Biology is *Slightly* More Challenging than Designing Electronics
Design Automation Tools For Metabolic Networks
Can principled engineering practices and design automation techniques for integrated circuits be applied when engineering biology?
This talk will draw some parallels between designing integrated circuits and engineering biological networks. The talk will showcase
several computational techniques (design automation tools) for designing and analyzing metabolic networks. A probabilistic algorithm
is shown to be competitive and significantly more efficient than exhaustive enumeration when identifying synthesis pathways.
Chance-constrained optimization is demonstrated effective in dealing with intervention uncertainties when tuning a cell to increase
the yield of target metabolites. Modularity analysis techniques are used to systematically identify biochemical reaction modules
that feature feedback motifs.
Soha Hassoun is an associate professor and Chair at Tufts University in the Department of Computer Science, with a joint appointment
in Electrical and Computer Engineering. She earned a Ph.D. from the Department of Computer Science and Engineering at the University
of Washington, Seattle, in 1997. Dr. Hassoun received a BSEE from South Dakota State University in 1986, and a Master's degree from
MIT in 1988. Her research interests lie in Electronic Design Automation and Bio Design Automation.
Soha was a recipient of an NSF CAREER Award and ACM/SIGDA Distinguished Service Awards for creating the Ph.D. forum at Design
Automation Conference (DAC), and the CADAthlon at ICCAD. She serves and has served on a number of technical and executive committees
for several conferences and workshops including serving as the technical program chair for the Design Automation Conference (DAC) in
2012 and 2011, and the International Conference on Computer-Aided Design (ICCAD) in 2005. She is a Tau Beta Pi fellow. She is a
member of ACM, a senior member of IEEE, and Eta Kappa Nu.
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